Biotechnology Resource CenterBioinformatics Facility(formerly the Computational Biology Service Unit or CBSU)

Bioinformatics Facility
  • Services include evaluating desktop and network needs, procuring and implementing appropriate computational infrastructure, and providing comprehensive bio-IT support for desktops and networks.  Click here for more information.

  • The BioHPC Computing Laboratory is a cloud computing resource configured for biologists.  It was developed and is maintained by the staff of the Bioinformatics Facility.  It provides investigators with direct access to a wide range of bioinformatics data analysis software tools.  Users can access the lab’s computers either remotely or on-site in the core (625 Rhodes Hall).  The lab has servers with configurations designed for different type of data analysis, including large memory servers for de novo sequence assembly analysis.  The core maintains many of the most commonly used data analysis software for next generation sequencing on the lab’s computers.  Click here for more information.  Click here to login to the BioHPC Computing Laboratory.

  • The facility procures, implements, maintains and provides access to many commercial and free software packages.  Click here for more information.

  • The facility offers project-based collaborations funded through either joint research grants or fee-for-services.  The facility staff currently participates in multiple research collaborations.  We welcome new collaborations and can work with you to apply for joint funding.  The facility provides collaborative support for large scale multidisciplinary research projects in close coordination with the genomics, proteomics, imaging, bio-IT, and advanced technology assessment cores facilities of the BRC.  Click here for more information.

  • Consultation services are available upon request or during office hours.  Coordinated project design consultation and data analysis support are available with the BRC genomics, proteomics, imaging, bio-IT, and advanced technology assessment core facilities.  Bioinformatics software analysis tools are available through the Bioinformatics Facility.  Click here for more information.

  • Next generation sequencing (NGS) data analysis services includes support for whole genome sequencing, targeted region sequencing, genotyping-by-sequencing (GBS), cDNA-based whole transcriptome, digital gene expression and small RNA discovery and analysis (RNA-Seq), sequencing of DNA fragments isolated by chromosome immunoprecipitation (ChIP-Seq), detection of DNA methylation (Meth-Seq), and many other applications.  The facility staff can help investigators with NGS data analysis using available software and can also develop customized software tools.  Click here for more information.

  • Bioinformatics support is available for both basic research and clinical research.  The bioinformatics facility supports bioinformatics analysis software and develops analysis pipelines for the diverse data types generated by all the BRC core facilities.  The facility also designs and hosts Laboratory Information Management Systems (LIMS) research databases.  Examples of such activities include: (1) designing database systems for specific research problems; (2) developing interfaces for data access, storage and analysis; and (3) deploying these applications on the core's computing resources.  The facility can help researchers integrate diverse data sets, such as genomics, proteomics, metabolomics and imaging information.  Databases can be designed to support basic research projects and clinical research studies.  Click here for more information.

  • The facility runs bioinformatics workshops that cover a wide range of topics, from an introduction to the Linux computing environment, to how to analyze next generation sequencing data.  Workshops include both lectures and hands-on sessions.  Click here for more information.